Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2017 | Month : August | Volume : 11 | Issue : 8 | Page : EC09 - EC11

Fine-Needle Aspiration of De Quervain's Thyroiditis (Subacute Granulomatous Thyroiditis): A Cytological Review of 20 Cases

Rachna Lamichaney, Mingma Sherpa, Deepak Das, Chumila Thinley Bhutia, Sabina Laishram

1. Assistant professor, Department of Pathology, SMIMS, Gangtok, Sikkim, India. 2. Associate professor, Department of Pathology, SMIMS, Gangtok, Sikkim, India. 3. Demonstrator, Department of Pathology, Jorhat Medical College, Jorhat, Assam, India. 4. Assistant Professor, Department of Pathology, SMIMS, Gangtok, Sikkim, India. 5. Assistant Professor, Department of Pathology, SMIMS, Gangtok, Sikkim, India.

Correspondence Address :
Dr. Mingma Sherpa,
Associate Professor, Department of Pathology, Sikkim Manipal Institute of Medical Sciences, Gangtok-737102, Sikkim, India.
Email : mingma.s@smims.smu.edu.in

Abstract

Introduction: De Quervain’s Thyroiditis (DQT) is a self limiting inflammatory disease of the thyroid gland that presents with pain and sore throat. Although the diagnosis is usually made clinically, Fine Needle Aspiration (FNA) may provide assistance, particularly in excluding other thyroid lesions.

Aim: The objective of this study was to reveal the cytological characteristics of DQT.

Materials and Methods: We retrospectively reviewed the clinical and FNAC findings of 20 cases of DQT to find the most reliable features for a confident cytological diagnosis.

Results: Among the cases reviewed, the common cytological features present in all 20 cases were follicular epithelial cells with degenerative changes and dirty background comprising of cellular debris and mixed inflammatory cells (lymphocytes and macrophages and occasional polymorphs). The next common finding observed was Multinucleated Giant Cells (MNGCs) seen in 19 cases followed by epithelioid cell clusters in 15 and colloid in 13 cases.

Conclusion: Presence of follicular epithelial cells, large MNGCs and dirty background of cellular debris, mixed inflammatory cells with predominance of lymphocytes and macrophages were the most striking and consistent features for diagnosis of DQT in cytological smears. The above findings in consideration with the clinical history will help us reach a definitive diagnosis. FNA also proves to be a useful tool in excluding other thyroid lesions with similar clinical presentations.

Keywords

Cytology, Degenerated follicular epithelial cells, Multinucleated giant cells

How to cite this article :

Rachna Lamichaney, Mingma Sherpa, Deepak Das, Chumila Thinley Bhutia, Sabina Laishram. FINE-NEEDLE ASPIRATION OF DE QUERVAIN'S THYROIDITIS (SUBACUTE GRANULOMATOUS THYROIDITIS): A CYTOLOGICAL REVIEW OF 20 CASES. Journal of Clinical and Diagnostic Research [serial online] 2017 August [cited: 2017 Nov 25 ]; 11:EC09-EC11. Available from
http://jcdr.in/back_issues.asp?issn=0973-709x&year=2017&month=August&volume=11&issue=8&page=EC09-EC11&id=10355

DOI and Others

DOI: 10.7860/JCDR/2017/26054.10355

Date of Submission: Dec 16, 2016
Date of Peer Review: Feb 06, 2017
Date of Acceptance: May 15, 2017
Date of Publishing: Aug 01, 2017

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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