Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

Users Online :

Original article / research
Year : 2017 | Month : August | Volume : 11 | Issue : 8 | Page : OC01 - OC04

Pattern of Allergen Sensitivity among Patients with Bronchial Asthma and/or Allergic Rhinosinusitis in a Tertiary Care Centre of Southern India

Bharti Chogtu, Neha Magaji, Rahul Magazine, Preetamtam R Acharya

1. Associate Professor, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India. 2. Senior Resident, Department of Pulmonary Medicine, M S Ramaiah Medical College, Bangalore, Karnataka, India. 3. Professor, Department of Pulmonary Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India. 4. Associate Professor, Department of Pulmonary Medicine, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India.

Correspondence Address :
Dr. Rahul Magazine,
Professor, Department of Pulmonary Medicine, Kasturba Medical College, Manipal University,
Manipal-576104, Karnataka, India.
E-mail: rahulmagazine@gmail.com

Abstract

Introduction: The distribution of aeroallergens varies among various geographical areas of India and the knowledge of allergen sensitivity pattern in this part of Southern Indian (Karnataka) is limited. This data can provide clinically useful information and better understanding of common allergies prevalent in this area.

Aim: To study the pattern of allergen sensitivity among patients with bronchial asthma and/or allergic rhinosinusitis.

Materials and Methods: In this retrospective study, patients diagnosed with bronchial asthma and/or allergic rhinitis who underwent skin prick testing, were included in the study. Patients who had taken drugs that could affect the test results, within one week prior to testing were excluded. Also, patients on long-acting oral antihistamines within four weeks of testing and pregnant women were excluded. A total of 64 antigens were used which included eight types of pollens, eight types of dusts, six types of fungi, eight types of insects, two types of danders, wool and 31 types of food items. Skin prick testing was done as per standard protocol.

Results: Out of 2219 patients, 1193 (53.8%) were males and 1026 (46.2%) were females. The mean age of the subjects was 41.47 (±14) years. There were 740 (33.3%) patients diagnosed with bronchial asthma, 357 (16.1%) allergic rhinitis and 1122 (50.6%) had both bronchial asthma and allergic rhinitis. Overall the highest percentage of skin-prick test positivity was found among insect allergens (24.45%) followed by dust (24.21%), grass and tree pollen (20.57%), fungus (13.92%) and food allergens (9.28%), in that order. Among the individual allergens, the highest percentage of skin-prick test positivity was present in rice grain dust allergen (33.30%) and the least common was chicken allergen (4.40%).

Conclusion: Among the allergen groups, insects and dusts elicited the highest percentage of skin-prick test positive results. Whereas, among all the individual allergens rice grain dust elicited highest percentage of positives.

Keywords

Aeroallergen, House dust mite, Skin prick test

How to cite this article :

Bharti Chogtu, Neha Magaji, Rahul Magazine, Preetamtam R Acharya. PATTERN OF ALLERGEN SENSITIVITY AMONG PATIENTS WITH BRONCHIAL ASTHMA AND/OR ALLERGIC RHINOSINUSITIS IN A TERTIARY CARE CENTRE OF SOUTHERN INDIA. Journal of Clinical and Diagnostic Research [serial online] 2017 August [cited: 2017 Nov 25 ]; 11:OC01-OC04. Available from
http://jcdr.in/back_issues.asp?issn=0973-709x&year=2017&month=August&volume=11&issue=8&page=OC01-OC04&id=10328

DOI and Others

DOI: 10.7860/JCDR/2017/26973.10328


Date of Submission: Jan 24, 2017
Date of Peer Review: Mar 25, 2017
Date of Acceptance: May 01, 2017
Date of Publishing: Aug 01, 2017


Financial OR OTHER COMPETING INTERESTS: None.

JCDR is now Monthly and more widely Indexed .
  • PubMed Central® (PMC)New
  • Academic Search Complete Database
  • Chemical Abstracts Service
  • Directory of Open Access Journals (DOAJ)
  • EBSCOhostNew
  • Embase & EMbiology
  • Google Scholar
  • HINARI Access to Research in Health Programme
  • Indian Science Abstracts (ISA)
  • Journal seek Database
  • Open J-Gate
  • Popline (reproductive health literature)
  • SCOPUS
  • www.omnimedicalsearch.com